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Grand Heartland Cruise

15 days with American Cruise Lines  Rating: Deluxe

Book this River Cruise Now and Save!


  • Enjoy a free open-bar cocktail hour every evening before dinner. Click here for eligible departures.
  • Save $400 per couple off American Cruise Lines departures when you book nine months in advance. Click here for eligible departures.
  • Receive free shore excursions on select river cruises. Click here for eligible departures.

Offers subject to change or withdrawal, availability is limited. Some discounts are not combinable.

River Cruise Itinerary
Day 1 St. Paul, MN
St. Paul is a thrilling place to begin your adventure on the Mississippi River. History buffs will enjoy a walking tour of Summit Avenue, which showcases gorgeous historic mansions built in the late 1800’s. St. Paul’s enchanting art galleries, world class museums, and entertaining stage performances will capture your imagination. be sure to visit Mounds Park for a beautiful panoramic view of the city.

Day 2 Red Wing, MN
Nestled among the scenic bluffs of the upper Mississippi River, Red Wing's beauty has inspired artisans, craftspeople and artists for over 150 years. Red Wing delivers a diverse blend of arts, entertainment and activities for your pleasure. Enjoy a show at the historic Sheldon Performing Arts Theatre or observe the beauty of nature at one of Red Wing’s 38 parks.

Day 3 La Crosse, WI
Step into 19th century America in La Crosse, located on the banks of three captivating rivers. La Crosse is home to Riverside Park, where you’ll enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures.

Day 4 Dubuque, IA
A “Masterpiece on the Mississippi,” Dubuque is among the oldest settlements west of the Mississippi River. Dubuque is overflowing with things to do and see. Take a ride on the Fenelon Place Elevator, the world’s shortest and steepest scenic railway or try your luck in one of Dubuque's state-of-the-art casinos. View colorful Victorian mansions, stroll through a whimsical downtown area, and visit the national Mississippi River Museum and Aquarium.

Day 5 Davenport, IA
Voted one of the Most Livable Small Cities in America, Davenport is often described by newcomers and life-long residents alike as a lively, active city with a hometown feel. This vibrant city features the Legacy of John Deere, the largest agricultural exhibit in the world. Music enthusiasts will enjoy Davenport’s many music festivals, including the Mississippi Valley Blues Festival, The Mississippi Valley Fair, and the Bix Beiderbecke Memorial Jazz Festival, which is dedicated to native jazz musician Bix Beiderbecke.

Day 6 Day of River Cruising
Enjoy the day relaxing on the upper deck, or your private balcony as we cruise from Davenport, IA to Hannibal, MO.

Day 7 Hannibal, MO
Hannibal, “America’s Hometown,” is a place where you can rediscover adventures from Mark Twain’s era. Tom Sawyer and Huck Finn are alive in this charming Missouri town, where you can run your hand along Aunt Polly’s fence, explore Injun Joe’s Cave, and get reacquainted with one of the world’s most beloved authors. The downtown area is a thriving haven for artisans filled with wonderful and special shops unique to Hannibal. No matter what you choose to do, you will find this town to be very accommodating.

Day 8 St. Louis, MO
St. Louis, known as the “Gateway to the West,” is sure to win you over. Take in the Gateway Arch Riverfront, highlighted by the majestic Gateway Arch, which is the largest manmade monument in the U.S. There’s something for everyone at St. Louis’ many world-class, free attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum. End your day by relaxing at the Missouri Botanical Garden, one of the world’s top public gardens.

Day 9 Day of River Cruising
Grab a good book and curl up in one of our spacious lounges, or grab a pair of binoculars and enjoy the fall foliage as we make our way down the Mississippi River.

Day 10 Memphis, TN
Excitement resonates as you reach America’s third-largest inland port, famous for blues, barbeque, and Elvis Presley's Graceland. Less-touted attractions, such as the Pink Palace and Mud Island’s River Walk, replicating 1,000 miles of Mississippi River history and geography along an intriguing six-block stroll, are just as intriguing. The Memphis-Arkansas Memorial Bridge creates a dramatic backdrop for it all. As you disembark, immerse yourself in the sights and sounds of one of the mid-South's most remarkable cities.

Day 11 Day of River Cruising
Spend a beautiful day with friends in one of the ship's beautiful lounges as we explore the river from Memphis to Vicksburg.

Day 12 Vicksburg, MS
Around every corner, U.S. history is alive in Vicksburg. This “Queen City of the Bluff” offers plenty of opportunities to take a step back in time. Civil war battlefields, century old churches, cotton fields, and restored train depots are just a few of the many intriguing landmarks that await your visit. Marvel in the beautiful antebellum-style homes and watch Vicksburg’s history come to life at the riverfront murals.

Day 13 Natchez, MS
Overlooking the Mississippi River, Natchez was first established as a French fort site in 1716, later becoming part of the United States as the first capital of Mississippi in 1817. Perched over 200 feet above the Mississippi River with 30-mile views along the river both north and south, the bluff of Natchez is a place to marvel in the beauty and grandeur of the river. A quaint Southern town rich in culture, history, and known for its abundance of antebellum architecture, Natchez offers true southern hospitality with the attractions of a great small city.

Day 14 Baton Rouge, LA
Baton Rouge, Louisiana’s state capital, was named over 300 years ago by French explorer Pierre Le Moyne d'Iberville. The city’s rich cultural traditions are reflected through its African-American and Caribbean influenced architecture, experienced through its fiery Creole and Cajun cuisine, and heard in its soulful Blues and Cajun style music. Baton Rouge is a wondrous city brimming with Southern hospitality.

Day 15 New Orleans, LA
Welcome to New Orleans, commonly referred to as the Birthplace of Jazz. There is something for everyone with this city’s history, culture and arts prevalent around every corner. The open air artist colony proudly displays local artist’s works on the iron fence in Jackson Square, while the city’s 45 museums carefully preserve the city’s rich history. Consider staying an extra day or night to enjoy this lively city.
Tour Map
All This Included
This epic journey on the world's newest riverboat transports guests back into American History as we spend two weeks cruising from St. Paul, MN to New Orleans, LA. 

Guests to visit 10 states in the most comfortable way possible. They will travel further thank even Huck Finn’s famous trip down the Mississippi - and experience northern fall foliage, southern hospitality, jazz, country, Graceland, barbeque, Cajun, Creole, the complete history of the Louisiana purchase, Civil War, and beginning of the Lewis and Clark expedition.
  • Dining service, snacks and complimentary cocktail parties.
  • Entertainment aboard the ship.
  • Oversized staterooms – largest in industry.
  • Most with private balconies.
  • Flat screen satellite TV and DVD players in all staterooms.
  • Wireless internet access shipwide.
  • Hairdryers in all staterooms.
  • Individual climate control in all staterooms.
Accommodations on this Tour
Category A cabin onboard the Queen of the Mississippi or America
Notes
  • Cabin upgrades are available.
  • Itinerary is subject to change.
  • Fares do not include shore tours, gratuities, or port charges and fees.
  • Please ask your Vacations To Go travel counselor for more information.
Terms and Conditions

* The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines. Sorry, we are unable to offer air from countries other than the U.S. However, for those international customers who are able to arrange their own transportation to the trip origination city, we are able to offer the land/cruise portion of the package at the price quoted.



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